Hormone

Hormones are special chemical messengers in the body that are created in the endocrine glands, being secreted directly into the blood, which carries them to organs and tissues of the body to exert their functions. They work slowly, over time, and affect many different processes, including (i) development and growth, (ii) metabolism of food items, (iii) sexual function and reproductive growth and health, (iv) cognitive function and mood, (v) maintenance of body temperature and thirst. Different endocrine ligands produce hormones, including but not limited to pituitary, pineal, hypothalamus, thyroid, thymus, and adrenal. They work together to maintain the hormone homeostasis. Even a very slight excess of hormone secretion can lead to disease states, as can the slightest deficiency in a hormone.

Diagnosis of Hormone Disorders

Hormone Disorders

Hormone disorders are problems arising from hormone imbalance, including hyposecretion and hypersecretion, which are diagnosed in the laboratory as well as by clinical appearance and features. Different diagnostic tests can be performed depending on the symptoms. First, blood tests can be performed to measure the level of various hormones and other protein biomarkers in the blood. In addition, other tests, including x-rays, magnetic resonance imaging (MRI), ultrasound scanning, can be performed to get images of the body endocrine glands and help diagnose hormone disorders. Moreover, point-of-care tests (POCTs) have also been extensively developed in recent years for disease detection and monitoring.

In Vitro Diagnostic (IVD) Antibody Development Services Provided by Creative Biolabs

Immunoassays are based on the highly specific molecular recognition of antibodies and antigens, enabling the sensitive detection of biomolecules. There are several commonly used immunoassays for hormone detection, including enzyme-linked immunosorbent assay (ELISA), chemiluminescence immunoassay (CLISA), and lateral flow assay (LFA). Development of immunoassays involves three major steps, which are (i) preparation of antigens, (ii) animal immunization to get antibodies, and (iii) establishment and validation of immunoassay protocols. The antibody is a key substance in establishing immunoassay technology and obtaining high-quality antibodies is of utmost importance. Moreover, the establishment and validation of immunoassay protocol is a time-consuming, resource-intensive effort.

As a well-recognized antibody service provider for research, diagnostic, and therapeutic purposes, Creative Biolabs has rich experience in the generation of high-quality antibody (pairs) targeting various hormones for IVD uses. We apply advanced antibody development technologies (e.g., hybridoma technology and phage display technology) to serve your specific project requirements. We also offer comprehensive customized engineering services of your antibodies to improve the performance and characteristics. Moreover, we provide one-stop diagnostic immunoassay development services, covering feasibility analysis, assay design, assay protocol establishment, validation, and kit production.

Please find more information about the hormone you are interested in by clicking the links below:

Features of Our Services

  • A specialized technical team and abundant experience in antibody development, engineering, and characterization
  • State-of-the-art antibody development technologies
  • Reasonable prices and short turnaround time
  • Services are tailored to meet the exact project needs of our valued clients.

Please feel free to contact us for more information and a formal quote.

Reference

  1. Tian, W., (2018). “Antibody production and application for immunoassay development of environmental hormones: a review.” Chemical and Biological Technologies in Agriculture, 5(1), 5.


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