An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. 

Autoimmune disease develops when your immune system, which defends your body against disease, decides your healthy cells are foreign. As a result, your immune system attacks healthy cells. Our bodies have an immune system, which is a complex network of special cells and organs that defends the body from germs and other foreign invaders. At the core of the immune system is the ability to tell the difference between self and nonself. A flaw can make the body unable to tell the difference between self and nonself. When this happens, the body makes autoantibodies that attack normal cells by mistake. At the same time special cells called regulatory T cells fail to do their job of keeping the immune system in line. The result is a misguided attack on your own body. This causes the damage we know as autoimmune disease. The body parts that are affected depend on the type of autoimmune disease. Nearly any body part can be involved, like the heart, brain, nerves, muscles, skin, eyes, joints, lungs, kidneys, glands, the digestive tract, and blood vessels.


Ordinarily, immune system produces antibodies (proteins that recognize and destroy specific substances) against harmful invaders-including: viruses, bacteria, parasites and fungi-in your body. When you have an autoimmune disease, your body produces antibodies against some of your own tissues. Diagnosing an autoimmune disease involves identifying the antibodies your body is producing:

  • Autoantibody tests: any of several tests that look for specific antibodies to your own tissues.
  • Antinuclear antibody tests: a type of autoantibody test that looks for antinuclear antibodies, which attack the nuclei of cells in your body.
  • Complete blood count: measures the numbers of red and white cells in your blood; when your immune system is actively fighting something, these numbers will vary from the normal.
  • C-reactive protein (CRP): elevated CRP is an indication of inflammation throughout your body erythrocyte sedimentation rate: this test indirectly measures how much inflammation is in your body.

There are at least 80 types of autoimmune diseases. Many of them have similar symptoms, which makes them very difficult to diagnose. It's also possible to have more than one at the same time.  

At Creative Biolabs, our seasoned scientists are confident in offering the custom IVD antibody discovery and development services for various biomarkers that from a broad range of autoimmune diseases, which including but not limited to:

Rheumatoid arthritis: inflammation of joints and surrounding tissues.
Mucous membrane pemphigoid: the autoimmune reaction occurs in the skin, specifically at the level of the basement membrane.
Childhood Asthma: leading cause of chronic illness in children, which can be caused by allergens, irritants, weather, exercise, infections, etc.
Systemic lupus erythematosus: affects skin, joints, kidneys, brain, and other organs.

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