Human EGFL7 Matched Antibody Pair set for ELISA useCapture Antibody: Rabbit purified polyclonal anti-EGFL7Detection Antibody: Mouse monoclonal anti-EGFL7, IgG2a Kappa
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Antigen Detail | |
|---|---|
| Target | EGFL7 |
| Description | EGF-like domain-containing protein 7 is a protein that in humans is encoded by the EGFL7 gene. Intron 7 of EGFL7 hosts the miR-126 microRNA gene. EGFL7 is a secreted protein and recently has been shown to play an important role in acute myeloid leukemia (AML). EGFL7 plays a vital role in controlling vascular angiogenesis during embryogenesis, organogenesis. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Mouse |
| Conjugation | Unconjugated |
| Clone | RD1069 |
| Isotype | IgG2a, kappa |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human EGFL7 Matched Antibody Pair set for ELISA use Capture Antibody: Rabbit purified polyclonal anti-EGFL7 Detection Antibody: Mouse monoclonal anti-EGFL7, IgG2a Kappa |
| Specificity | Validated for detecting natural and recombinant human EGFL7 |
| Research Area | Vasculature |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | EGFL7 |
| Full Name | EGF-like domain-containing protein 7 |
| Background | EGF-like domain-containing protein 7 is a protein that in humans is encoded by the EGFL7 gene.[5] Intron 7 of EGFL7 hosts the miR-126 microRNA gene. |
| Alternative Names | EGFL7; NEU1; VE-STATIN; ZNEU1; EGF like domain multiple 7 |
| Gene ID | 51162 |
| Uniprot ID | Q9UHF1 |
| GeneCards | EGFL7 |
| HGNC | 20594 |
| Ensembl | ENSG00000172889 |
| OMIM | 608582 |
| Involvement in Disease | Diseases associated with EGFL7 include?Carotid Artery Disease. Gene Ontology (GO) annotations related to this gene include?calcium ion binding?and?Notch binding. An important paralog of this gene is?EGFL8. |
| Function | Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis |
For Research Use Only.
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