Human FGD3 Matched Antibody Pair set for ELISA useCapture Antibody: Rabbit purified polyclonal anti-FGD3Detection Antibody: Mouse monoclonal anti-FGD3, IgG1 Kappa
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Antigen Detail | |
|---|---|
| Target | FGD3 |
| Description | FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene. Expression of the FGD3 gene is a strong marker of good prognosis in breast cancer patients and that immunohistochemistry represents an efficient, inexpensive, reproducible evaluation method. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Mouse |
| Conjugation | Unconjugated |
| Clone | RD10432 |
| Isotype | IgG1, kappa |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human FGD3 Matched Antibody Pair set for ELISA use Capture Antibody: Rabbit purified polyclonal anti-FGD3 Detection Antibody: Mouse monoclonal anti-FGD3, IgG1 Kappa |
| Specificity | Validated for detecting natural and recombinant human FGD3 |
| Research Area | Cytoskeleton |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | FGD3 |
| Full Name | FYVE, RhoGEF And PH Domain Containing 3 |
| Alternative Names | Zinc Finger FYVE Domain-Containing Protein 5 |
| Gene ID | 89846 |
| Uniprot ID | Q5JSP0 |
| GeneCards | FGD3 |
| HGNC | 16027 |
| Ensembl | ENSG00000127084 |
| OMIM | 617554 |
| Involvement in Disease | Diseases associated with FGD3 include Aarskog-Scott Syndrome and Charcot-Marie-Tooth Disease, Type 4H. |
| Function | Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity). |
| Related Pathways | Its related pathways are Signaling by GPCR and Actin Nucleation by ARP-WASP Complex. |
For Research Use Only.
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