Human FGF9 antibody pair set for sandwich ELISA useCapture Antibody: Monoclonal IgGDetection Antibody: Unconjugated-Rabbit Monoclonal IgG
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Antigen Detail | |
|---|---|
| Target | FGF9 |
| Description | Glial activating factor is a protein encoded by FGF9 gene in humans. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members have a wide range of mitogenic and cell survival activities, and participate in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The protein was isolated as a secreted factor that exhibited growth-stimulating effects on cultured glial cells. In the nervous system, this protein is mainly produced by neurons and may be important for the development of glial cells. It was found that the expression of mouse homologues of this gene depends on the signal of sonic hedgehog (Shh). Mice lacking homologous genes show opposite phenotypes of men and women, suggesting their role in testicular embryogenesis. This gene is involved in sex determination, lung development and bone development patterns. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone | IV01748 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Rabbit |
| Conjugation | Unconjugated |
| Clone | RD10497 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, BSA and Azide free |
General Product Property | |
|---|---|
| Product Overview | Human FGF9 antibody pair set for sandwich ELISA use Capture Antibody: Monoclonal IgG Detection Antibody: Unconjugated-Rabbit Monoclonal IgG |
| Specificity | Both the capture and the detection antibodies in this set react with Human FGF9 . |
| Range | 31.25 pg/mL-2000 pg/mL |
| Research Area | Immunology; Cell Biology; Cancer; Inflammation |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | FGF9 |
| Full Name | Glia-activating factor |
| Background | Glial activating factor is a protein encoded by FGF9 gene in humans. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members have a wide range of mitogenic and cell survival activities, and participate in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The protein was isolated as a secreted factor that exhibited growth-stimulating effects on cultured glial cells. In the nervous system, this protein is mainly produced by neurons and may be important for the development of glial cells. It was found that the expression of mouse homologues of this gene depends on the signal of sonic hedgehog (Shh). Mice lacking homologous genes show opposite phenotypes of men and women, suggesting their role in testicular embryogenesis. This gene is involved in sex determination, lung development and bone development patterns. |
| Alternative Names | FGF9; FGF-9; GAF; HBFG-9; HBGF-9; SYNS3; fibroblast growth factor 9 |
| GeneCards | FGF9 |
| HGNC | 3687 |
| Ensembl | ENSG00000102678 |
| OMIM | 600921 |
| Involvement in Disease | Diseases associated with FGF9 include Multiple Synostoses Syndrome 3 and Multiple Synostoses Syndrome. |
| Function | May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. |
| Related Pathways | Its related pathways are RET signaling and Signaling by FGFR2 in disease. |
For Research Use Only.
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