SARS-CoV-2 Spike protein antibody pair set for ELISA useCapture Antibody: Mouse Monoclonal IgG1Detection Antibody: Mouse Monoclonal IgG
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Antigen Detail | |
|---|---|
| Target | Spike protein |
| Description | Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests. |
| Species Reactivity | SARS-CoV-2 |
| Pathogen | Virus |
| Pathogen Family | Coronaviridae |
| Pathogen Species | SARS-CoV-2 |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Mouse |
| Clone | IV01182 |
| Isotype | IgG1 |
| Purification | Affinity Chromatography |
| Buffer | 50% Glycerol, 0.01M PBS, PH 7.4 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Mouse |
| Conjugation | HRP |
| Clone | RD1042 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | 50% Glycerol, 0.01M PBS, PH 7.4 |
General Product Property | |
|---|---|
| Product Overview | SARS-CoV-2 Spike protein antibody pair set for ELISA use Capture Antibody: Mouse Monoclonal IgG1 Detection Antibody: Mouse Monoclonal IgG |
| Specificity | Both the capture and the detection antibodies in this set react with SARS-CoV-2 Spike protein. |
| Research Area | Inflammation |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | S |
| Full Name | Spike Protein |
| Background | Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests. |
| Alternative Names | Spike Protein; S protein |
| Gene ID | 43740568 (Human) |
| Uniprot ID | P0DTC2 (Human) |
| Function | May down-regulate host tetherin (BST2) by lysosomal degradation, thereby counteracting its antiviral activity. |
For Research Use Only.
Application
