Small interfering RNA (siRNA), Anti-Human PHOSPHO1, 2ʹ-deoxy-2ʹ-fluoro (2'-F) Modified(CAT#: SIRGT62025WQ-2F)
The product SIRGT62025WQ-2F is a type of small interfering RNA (siRNA) that targets PHOSPHO1 gene and regulates the expression of gene. The siRNA interferes with the expression of PHOSPHO1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
Specifications | |
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Modification | 2ʹ-deoxy-2ʹ-fluoro (2'-F) |
Scale | 20/50/100/200 nmole |
NCBI RefSeq | NM_001143804.1 |
Related Diseases | Charcot-Marie-Tooth Disease |
Purification | HPLC |