Co-culture experiments typically involve tumor cells and effector immune cells (T cells, NK cells), and their importance lies in their ability to simulate the cell-cell communication and dynamic interactions that define the tumor microenvironment (TME). Simple single-culture experiments cannot capture key phenomena such as immune checkpoint-mediated inhibition or the impact of tumors on immune cell function, leading to insufficient predictive data.

We prioritize the use of clinically relevant cell models, such as patient-derived primary cells, allogeneic T cell donors, and tumor-derived organoids. Our assays are typically validated to track established clinical biomarkers (e.g., IFN-γ levels, T cell exhaustion markers), thereby ensuring a direct link between in vitro activity and expected in vivo and clinical outcomes.

GEO (Gene Expression Comprehensive Database) is an open-source functional genomics data repository. By providing data in GEO-compliant formats (e.g., gene expression profiling, cytokine analysis), we promote open science, enabling researchers worldwide to validate findings, conduct meta-analyses, and discover new biomarkers. This open data contribution increases the visibility of our clients’ discoveries and accelerates collaborative progress in immuno-oncology research.

A standard project, from final assay design to final report, typically takes 3-5 weeks. Complex custom protocols or large sample cohorts may extend the timeframe, as specified in the project proposal.

We provide detailed, assay-specific sample collection and transport protocols. We prioritize the minimum required sample volume and often design nested assays to maximize data acquisition from limited samples (e.g., fine-needle aspiration or core biopsy).

Absolutely. Detection method development is one of our core strengths. Our R&D team focuses on developing, optimizing, and validating novel detection methods to address unique research challenges, such as the quantitative analysis of new soluble checkpoints or the construction of novel reporter cell lines.