Small Interfering RNA (siRNA)

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Small Interfering RNA (siRNA)


Upon the discovery of RNA interference (RNAi), small interfering RNA (siRNA) has been recognized to regulate the expression of genes and gained attention as a potential therapeutic reagent in many genetic diseases. The siRNA is a class of double-stranded, non-coding RNA molecules, usually about 20-25 base pairs long. By RNA interference pathway, the siRNA is either loaded onto RISC directly or utilizes a Dicer mediated process, thereby initiating the RNAi process via targeting mRNA cleavage and degradation. Based on the outstanding expertise and rich experience, Creative Biolabs has the expertise and ability in providing abundant siRNA products with the best quality to advance our global clients’ projects.

Small Interfering RNA (siRNA) Figure 1. Schematic of siRNA-mediated RNAi mechanism. (Maria, 2019)

Creative Biolabs is dedicated to establishing the most exquisite service platform for RNAi therapy. We have sophisticated equipment and highly experienced staff, which is able to provide you with custom siRNA services that allows for flexibility in experimental initiation. From the foremost project design to the final products, we implement stringent criteria to guarantee the reliability and quality. The siRNA with custom modifications is also available to ensure specificity and reduce off-target effects. A series of ready-to-use siRNA products have been developed in house and we also offer the right reagent to efficient siRNA transfection.

Features of Our Custom siRNA Products

We also provide custom siRNA synthesis service, producing highly pure siRNA in diverse amounts (nmol) and offer various combinations of sizes, modifications, and purifications for convenient online ordering.

If you are interested in our service, please contact us by E-mail and our team will get back to you as soon as possible.

Reference

  1. Raja, M.; et al. (2019). Design, mechanism, delivery and therapeutics of canonical and Dicer-substrate siRNA. Asian Journal of Pharmaceutical Sciences, 14(5), pp.497-510.

For Lab Research Use Only, Not for Human or Animal Therapeutic Use.

Species: Human
Target: A1BG
Species: Human
Target: A2M
Species: Human
Target: NAT1
Species: Human
Target: NAT2
Species: Human
Target: SERPINA3
Species: Human
Target: AADAC
Species: Human
Target: AAMP
Species: Human
Target: AANAT
Species: Human
Target: AARS
Species: Human
Target: ABAT
Species: Human
Target: ABCA1
Species: Human
Target: ABCA2
Species: Human
Target: ABCA3
Species: Human
Target: ABCB7
Species: Human
Target: ABCA4
Species: Human
Target: ABL1
Species: Human
Target: AOC1
Species: Human
Target: ABL2
Species: Human
Target: ABO
Species: Human
Target: ACAA1

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For Lab Research Use Only, Not for Human or Animal Therapeutic Use.

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