siRNA, Anti-Human AIRE, LNA(CAT#: SIRGT04213WQ-LNA)

The product SIRGT04213WQ-LNA is a type of small interfering RNA (siRNA) that targets AIRE gene and regulates the expression of gene. The siRNA interferes with the expression of AIRE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_000383.3
Alternative Names AIRE1; APECED; APS1; APSI; PGA1
Related Diseases Reversible Metaphyseal Dysplasia, Hypoparathyroidism
Purification HPLC
Target Gene
Gene ID 326
Uniprot ID O43918

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