siRNA, Anti-Human APAF1, LNA(CAT#: SIRGT04205WQ-LNA)

The product SIRGT04205WQ-LNA is a type of small interfering RNA (siRNA) that targets APAF1 gene and regulates the expression of gene. The siRNA interferes with the expression of APAF1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001160.2; NM_013229.2; NM_181861.1; NM_181868.1; NM_181869.1
Alternative Names APAF-1; CED4
Related Diseases Dystrophinopathies, Retinal Ischemia
Purification HPLC
Target Gene
Gene ID 317
Uniprot ID O14727

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