siRNA, Anti-Human APEX1, 2'-OMe(CAT#: SIRGT01215WQ-2OMe)
The product SIRGT01215WQ-2OMe is a type of small interfering RNA (siRNA) that targets APEX1 gene and regulates the expression of gene. The siRNA interferes with the expression of APEX1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2ʹ-O-methyl (2'-OMe) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_001244249.1; NM_001641.3; NM_080648.2; NM_080649.2 |
| Alternative Names | APE; APE1; APEN; APEX; APX; HAP1; REF1 |
| Related Diseases | Pediatric T-Cell Leukemia, Attenuated Familial Adenomatous Polyposis |
| Purification | HPLC |
