siRNA, Anti-Human APRT, 2'-MOE(CAT#: SIRGT03236WQ-2MOE)
The product SIRGT03236WQ-2MOE is a type of small interfering RNA (siRNA) that targets APRT gene and regulates the expression of gene. The siRNA interferes with the expression of APRT gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
Specifications | |
---|---|
Modification | 2'-O-methoxyethyl (2'-MOE) |
Scale | 20/50/100/200 nmole |
NCBI RefSeq | NM_000485.2; NM_001030018.1 |
Alternative Names | AMP; APRTD |
Related Diseases | Adenine Phosphoribosyltransferase Deficiency, Lesch-Nyhan Syndrome |
Purification | HPLC |