siRNA, Anti-Human LDLR, 2'-F(CAT#: SIRGT12563WQ-2F)
The product SIRGT12563WQ-2F is a type of small interfering RNA (siRNA) that targets LDLR gene and regulates the expression of gene. The siRNA interferes with the expression of LDLR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2ʹ-deoxy-2ʹ-fluoro (2'-F) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_000527.4; NM_001195798.1; NM_001195799.1; NM_001195800.1; NM_001195803.1 |
| Alternative Names | FH; FHC; LDLCQ2 |
| Related Diseases | Homozygous Familial Hypercholesterolemia |
| Purification | HPLC |
