siRNA, Anti-Human SPAST, LNA(CAT#: SIRGT24370WQ-LNA)

The product SIRGT24370WQ-LNA is a type of small interfering RNA (siRNA) that targets SPAST gene and regulates the expression of gene. The siRNA interferes with the expression of SPAST gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_014946.3; NM_199436.1
Alternative Names ADPSP; FSP2; SPG4
Related Diseases Autosomal dominant spastic paraplegia 4
Purification HPLC
Target Gene
Gene ID 6683
Uniprot ID Q9UBP0

Related Products