siRNA, Anti-Human SQSTM1, LNA(CAT#: SIRGT29639WQ-LNA)

The product SIRGT29639WQ-LNA is a type of small interfering RNA (siRNA) that targets SQSTM1 gene and regulates the expression of gene. The siRNA interferes with the expression of SQSTM1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001142298.1; NM_001142299.1; NM_003900.4
Alternative Names A170; DMRV; FTDALS3; NADGP; OSIL; PDB3; ZIP3; p60; p62; p62B
Related Diseases Sporadic and familial Paget disease of bone
Purification HPLC
Target Gene
Gene ID 8878
Uniprot ID Q13501

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