Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsComputer simulation is a promising approach that allows the visualization of molecular structure modeling and docking. Based on this technique, Creative Biolabs provides high-quality services of molecular modeling and docking and helps our customers comprehensively understanding the chemical and topological features of the enzyme binding site and the basis of enzyme and its substrate recognition.
The enzyme binding site is a region that binds to its substrate with specificity. The function of enzyme catalysis lies in the specific binding of an enzyme and its substrate which is determined by the amino acid sequence and the structure of the substrates. In order to better understand the structure and function of the enzyme and accelerate enzyme design, in silico technique is used, which can perform molecular modeling, docking, and molecular dynamics simulation on the computer. Currently, energy functions are widely used for enzyme-substrate binding prediction, which can rank and score enzyme-substrate binding site predictions because binding involves a trade-off between the lowest-energy conformations of the free enzyme and the lowest-energy conformation of enzyme-substrate binding complex.
Fig.1 Docked complex of UGT with kaempferol and UDP-glucose. (Sharma, 2014)
We have accumulated extensive experience in molecular modeling, docking, and molecular dynamics simulation and are confident in offering a full range of one-stop enzyme-substrate binding site analysis services with high quality and low cost for global customers. We not only discover the potential inhibitors of an enzyme by computational docking analysis using PyRx, AutoDock Vina option based on scoring functions but also explore the enzyme binding site feature and substrate selectivity through molecular modeling, docking and dynamics simulation studies. Besides, we are also capable of designing and customizing personalized computational docking analysis scheme according to your special requirement.
With years of experience in computational ligand-target docking studies, Creative Biolabs is committed to offering comprehensive services of enzyme binding site analysis based on molecular modeling and docking. We have served a number of customers and won a good reputation in the in silico-based enzyme binding site analysis. If you are interested in our services, please don't hesitate to contact us and discuss your project.
Reference
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
