ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-Y0503	Bromo-PEG5-azide	1402411-90-8		370.2	95%		Inquiry
ADC-L-Y0506	Bromo-PEG3-bromide	31255-26-2		320	95%		Inquiry
ADC-L-Y0507	Bromo-PEG4-bromide	57602-02-5		364.1	95%		Inquiry
ADC-L-Y0508	Bromo-PEG5-bromide	67705-77-5		408.1	95%		Inquiry
ADC-L-Y0509	Bromo-PEG6-bromide	72713-23-6		452.2	95%		Inquiry
ADC-L-Y0511	3-(2-bromoacetamido)propanoic acid	89520-11-6		210	95%		Inquiry
ADC-L-Y0512	Bromoacetamido-PEG2-acid	1415800-44-0		298.1	95%		Inquiry
ADC-L-Y0513	Bromoacetamido-PEG3-acid	1807534-79-7		342.2	95%		Inquiry
ADC-L-Y0514	Bromoacetamido-PEG4-acid	1807518-67-7		386.2	95%		Inquiry
ADC-L-Y0515	Bromoacetamido-PEG8-acid	1698019-89-4		562.5	95%		Inquiry
ADC-L-Y0516	2-Bromo-2,2-dimethyl-acetamido-PEG3-acid	2279944-67-9		370.2	95%		Inquiry
ADC-L-Y0517	17-(Bromoacetamido-PEG9-ethylcarbamoyl)heptadecanoic acid			874	95%		Inquiry
ADC-L-Y0519	Bromoacetamido-PEG2-NHS ester	1353011-78-5		395.2	95%		Inquiry
ADC-L-Y0521	Bromoacetamido-PEG2-azide	86770-72-1		295.1	95%		Inquiry
ADC-L-Y0522	Bromoacetamido-PEG3-azide	940005-81-2		339.2	95%		Inquiry
ADC-L-Y0523	Bromoacetamido-PEG5-azide	1415800-37-1		427.3	95%		Inquiry
ADC-L-Y0525	Bromoacetamido-PEG4-t-butyl ester	1807521-00-1		442.4	95%		Inquiry
ADC-L-Y0526	Bromoacetamido-PEG8-t-butyl ester	2055041-16-0		618.6	95%		Inquiry
ADC-L-Y0527	17-(Bromoacetamido-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester			797.9	95%		Inquiry
ADC-L-Y0528	17-(Bromoacetamido-PEG9-ethylcarbamoyl)pentanoic t-butyl ester			761.8	95%		Inquiry