The product is a highly efficient, inducible Cas9 D10A (Nickase)-ABCA4 gene-editing based novel AAV packaging system that can be used to mediate researches involving anti-CXCR3 mab (1Q5Ch) in Human B cell engineering.
| Clone | 1Q5Ch |
| Host | Chimeric (mouse/human) |
| Packaging Cell Line | HEK 293 |
| Vector Promoter | EF1a |
| Rep | Rep78 |
| Capsid | P24 |
| Envelope | VSV-G |
| Matrix | N-terminal |
| Size | ~18kb |
| Genome | ssRNA |
| Virus Type | AAV |
| Cofactor Requirement | No ATP, CP, or CPK |
| Particles/mL | 7.2 × 10¹¹ |
| PFU/mL | 3.3 × 10¹¹ |
| TU/mL | 3.6 × 10¹¹ |
| Cas9 | Cas9 D10A (Nickase) |
| sgRNA | ABCA4 |
| Engineered B Cell | Human B cells |
| Target | CXCR3 |
| Alternative Names | CXCR3; chemokine (C-X-C motif) receptor 3; GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R; C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; Mig receptor; IP10 receptor; IP-10 receptor; G protein-coupled receptor 9; chemokine (C-X-C) receptor 3; interferon-inducible protein 10 receptor |
| Gene ID | 2833(Human); 12766(Mouse); 84475(Rat) |
| UniProt ID | P49682(Human); O88410(Mouse); Q9JII9(Rat) |
| Format | Liquid |
| Shipping | The product is shipped by dry ice. |
| Storage | Upon receipt, store immediately at -80°C or lower for long-term storage. Avoid freeze/thaw cycles. |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.