The product is a highly efficient, inducible Cas9 D10A H840A (Dead)-ASGR1 gene-editing based novel AAV packaging system that can be used to mediate researches involving anti-IL25 mab (2Uc3IRH2) in Human B cell engineering.
| Clone | 2Uc3IRH2 |
| Host | Chimeric (mouse/human) |
| Packaging Cell Line | HEK 293 |
| Vector Promoter | EF1a |
| Rep | Rep78 |
| Capsid | P24 |
| Envelope | VSV-G |
| Matrix | N-terminal |
| Size | ~20kb |
| Genome | dsRNA |
| Virus Type | AAV |
| Cofactor Requirement | No dNTPs |
| Particles/mL | 1.9 × 10¹¹ |
| PFU/mL | 9.7 × 10¹¹ |
| TU/mL | 6.5 × 10¹¹ |
| Cas9 | Cas9 D10A H840A (Dead) |
| sgRNA | ASGR1 |
| Engineered B Cell | Human B cells |
| Target | IL25 |
| Alternative Names | IL17E; interleukin-25; interleukin-17E |
| Format | Liquid |
| Shipping | The product is shipped by dry ice. |
| Storage | Upon receipt, store immediately at -80°C or lower for long-term storage. Avoid freeze/thaw cycles. |
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