The product is a highly efficient, inducible WT Cas9-Abca1 gene-editing based novel AAV packaging system that can be used to mediate researches involving anti-MMP14 mab (DX-2U5S3) in Human B cell engineering.
| Clone | DX-2U5S3 |
| Host | Humanized |
| Packaging Cell Line | HEK 293 |
| Vector Promoter | CMV |
| Rep | Rep78 |
| Capsid | P24 |
| Envelope | VSV-G |
| Matrix | N-terminal |
| Size | ~30kb |
| Genome | ssRNA |
| Virus Type | AAV |
| Cofactor Requirement | No dNTPs |
| Particles/mL | 7.2 × 10¹¹ |
| PFU/mL | 1.1 × 10¹¹ |
| TU/mL | 5.5 × 10¹¹ |
| Cas9 | WT Cas9 |
| sgRNA | Abca1 |
| Engineered B Cell | Human B cells |
| Target | MMP14 |
| Alternative Names | MMP14; MMP-14; MMP-X1; MT-MMP; MT-MMP 1; MT1-MMP; MT1MMP; MTMMP1; WNCHRS; matrix metallopeptidase 14 |
| Format | Liquid |
| Shipping | The product is shipped by dry ice. |
| Storage | Upon receipt, store immediately at -80°C or lower for long-term storage. Avoid freeze/thaw cycles. |
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