The product is a highly efficient, inducible WT Cas9-Abca1 gene-editing based novel AAV packaging system that can be used to mediate researches involving anti-NGF mab (MEDI-57N11V) in Monkey B cell engineering.
| Clone | MEDI-57N11V |
| Host | Humanized |
| Packaging Cell Line | GP-293 |
| Vector Promoter | EF1a |
| Rep | Rep68 |
| Capsid | P24 |
| Envelope | GP120 |
| Matrix | N-terminal |
| Size | ~10kb |
| Genome | dsDNA |
| Virus Type | AAV |
| Cofactor Requirement | No dNTPs |
| Particles/mL | 2.6 × 10¹¹ |
| PFU/mL | 1.6 × 10¹¹ |
| TU/mL | 5.4 × 10¹¹ |
| Cas9 | WT Cas9 |
| sgRNA | Abca1 |
| Engineered B Cell | Monkey B cells |
| Format | Liquid |
| Shipping | The product is shipped by dry ice. |
| Storage | Upon receipt, store immediately at -80°C or lower for long-term storage. Avoid freeze/thaw cycles. |
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