This product is a U266B1 [U266] B cell engineering tool based on the Magnetic nanoparticles (LRP-1 targetingpeptide/Lipoproteinreceptor-related protein-1) delivery system and CRISPR-based (SHS-323-crRNA:tracrRNA duplex-Cas9-Brefeldin A ) genome editor.
| Host Cell | U266B1 [U266] |
| Target | ACE2 |
| Insert Clone | CBYC-A206 |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Magnetic nanoparticles |
| Ligand/Receptor | LRP-1 targeting peptide/Lipoprotein receptor-related protein-1 |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | 10-50 |
| Charge (mv) | −15 to -185 |
| Total Atom Count | ~20,000,000 |
| Surface Atoms (%) | ~4 |
| Specific Surface Area (m2/g) | ~8 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Lung cancer; Breast cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.