The product is a highly efficient, inducible WT Cas9-ASGR1 gene-editing based novel Adenovirus packaging system that can be used to mediate researches involving anti-DSC1 mab (VH3I-0J10L) in Human B cell engineering.
| Clone | VH3I-0J10L |
| Host | Humanized |
| Packaging Cell Line | HEK 293 |
| Vector Promoter | EF1a |
| Rep | Rep78 |
| Capsid | P24 |
| Envelope | VSV-G |
| Matrix | N-terminal |
| Size | ~18kb |
| Genome | ssRNA |
| Virus Type | Adenovirus |
| Cofactor Requirement | No Mg²⁺ |
| Particles/mL | 1.6 × 10¹¹ |
| PFU/mL | 4.8 × 10¹¹ |
| TU/mL | 3.4 × 10¹¹ |
| Cas9 | WT Cas9 |
| sgRNA | ASGR1 |
| Engineered B Cell | Human B cells |
| Target | DSC1 |
| Alternative Names | DSC1; CDHF1; DG2/DG3; desmocollin 1 |
| Format | Liquid |
| Shipping | The product is shipped by dry ice. |
| Storage | Upon receipt, store immediately at -80°C or lower for long-term storage. Avoid freeze/thaw cycles. |
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