The product is a highly efficient, inducible Cas9 D10A (Nickase)-ASGR1 gene-editing based novel Adenovirus packaging system that can be used to mediate researches involving anti-FCGR2B mab (CH2UB7Y) in Human B cell engineering.
| Clone | CH2UB7Y |
| Host | Humanized |
| Packaging Cell Line | CHO |
| Vector Promoter | CMV |
| Rep | Rep40 |
| Capsid | P24 |
| Envelope | VSV-G |
| Matrix | N-terminal |
| Size | ~8kb |
| Genome | ssRNA |
| Virus Type | Adenovirus |
| Cofactor Requirement | No Mg²⁺ |
| Particles/mL | 6.1 × 10¹¹ |
| PFU/mL | 4.4 × 10¹¹ |
| TU/mL | 2.3 × 10¹¹ |
| Cas9 | Cas9 D10A (Nickase) |
| sgRNA | ASGR1 |
| Engineered B Cell | Human B cells |
| Target | FCGR2B |
| Alternative Names | Fc Fragment Of IgG Receptor IIb; Fc Fragment Of IgG; Low Affinity IIb; Receptor (CD32); Fc Fragment Of IgG; Low Affinity IIb; Receptor For (CD32); Fc Gamma Receptor IIb; IgG Fc Receptor II-B; Fc-Gamma RII-B; Fc-Gamma-RIIb; FcRII-B; CDw32; IGFR2; FCG2; CD32; Fc Fragment Of IgG; Low Affinity II; Receptor For (CD32); Fc Gamma RIIb; CD32 Antigen; FCGR2; CD32B |
| Gene ID | 14130(Mouse) |
| UniProt ID | P08101(Mouse) |
| Format | Liquid |
| Shipping | The product is shipped by dry ice. |
| Storage | Upon receipt, store immediately at -80°C or lower for long-term storage. Avoid freeze/thaw cycles. |
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