This product is a SU-DHL-6 B cell engineering tool based on the Sphingosomes (MUC1 aptamer/MUC1) delivery system and CRISPR-based (AAVS1-SpCas9-NLS-Cas9-(Z)-4-Hydroxytamoxifen ) genome editor.
| Host Cell | SU-DHL-6 |
| Target | AFP |
| Insert Clone | 10C232 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | (Z)-4-Hydroxytamoxifen |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Sphingosomes |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | Celastrol |
| Particle Size | <2500 |
| Charge (mv) | −10 to -50 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Breast cancer; Colon cancer; Lung cancer; Ovarian cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.