This product is a BC-1 B cell engineering tool based on the Solid lipid nanoparticles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (hROSA26-crRNA:tracrRNA duplex-Cas12-RS-1 ) genome editor.
| Host Cell | BC-1 |
| Target | AFP |
| Insert Clone | 1G7 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | 20-150 |
| Charge (mv) | −15 to -185 |
| Total Atom Count | ~60,000,000 |
| Surface Atoms (%) | ~0.8 |
| Specific Surface Area (m2/g) | ~2.5 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Breast cancer; Colon cancer; Lung cancer; Ovarian cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.