This product is a Raji B cell engineering tool based on the Sphingosomes (EpCAM aptamer/Epithelial celladhesion molecule) delivery system and CRISPR-based (AAVS1-SpCas9-NLS-Cas9-(Z)-4-Hydroxytamoxifen ) genome editor.
| Host Cell | Raji |
| Target | AFP |
| Insert Clone | 214107 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | (Z)-4-Hydroxytamoxifen |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-1 |
| Vehicles | Sphingosomes |
| Ligand/Receptor | EpCAM aptamer/Epithelial cell adhesion molecule |
| Active Agents | Celastrol |
| Particle Size | 20-3500 |
| Charge (mv) | −11 to -345 |
| Total Atom Count | ~60,000,000 |
| Surface Atoms (%) | ~0.8 |
| Specific Surface Area (m2/g) | ~2.5 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Breast cancer; Colon cancer; Lung cancer; Ovarian cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.