This product is a B cell engineering plasmid designed by genomic integration of B cell receptors (Luc-MNDU3-Sec/SPIII-CD79α-CD8-CBP) and CRISPR-Cas (Cas12b (C2c1)-RNA-HD/Cas10-Stat5a) systems.
| Clone | 7C37 |
| Host | Humanized |
| Targeting Cell Type | Ramos (RA 1) |
| Reporter gene | GUS |
| Promoter | MNDU3 |
| Signal peptides | Sec/SPIII |
| Signaling domains | CD79α |
| TM domains | CD8 |
| Detection tags | CBP |
| Linkers | Thioredoxin with polylinker |
| Co-Receptors | CD72 |
| Vector Type | Adenoviruses |
| Vector Name | BGpCDH3 |
| Class | 2 single-Cas |
| Type | IV |
| Subtype | A, B, C |
| Effector | Cas12b (C2c1) |
| DNA Type | RNA |
| Nuclease domains | HD/Cas10 |
| TracrRNA requirement | YES |
| PAM/PFS | - |
| Insertion | Stat5a |
| Construction | GUS-MNDU3-CD79α-Cas12b (C2c1)-RNA-Stat5a |
| Format | Liquid/lyophilized |
| Shipping | It is usually shipped overnight at room temperature in small cardboard boxes. If hot temperatures are expected during transit, they will be shipped in polystyrene containers with gel ice packs. |
| Handling Advice | No special measures are necessary. Keep away from food, drink and animal feedingstuffs. |
| Storage | Plasmid (lyophilized), short-time storage at Room Temperature, recommended store at -20°C or -80°C ; Plasmid (Liquid), blue ice store at 4°C. |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.