This product is a Raji-Luc2 B cell engineering tool based on the Niosomes (LRP-1 targeting peptide/Lipoprotein receptor-related protein-1) delivery system and CRISPR-based (AAVS1-sgRNA-Cpf1-Nocodazole) genome editor.
| Host Cell | Raji-Luc2 |
| Target | AXL |
| Insert Clone | BG-12B |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH responsive |
| Insertion sites | Mouse genome E-6 |
| Vehicles | Niosomes |
| Ligand/Receptor | LRP-1 targeting peptide/Lipoprotein receptor-related protein-1 |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | <2300 |
| Charge (mv) | 3 to 20 |
| Total Atom Count | -22000000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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