This product is a Raji B cell engineering tool based on the Solid lipid nanoparticles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (AAVS1-crRNA:tracrRNA duplex-Cas12-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Raji |
| Target | C12orf40 |
| Insert Clone | 5H4C |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | <500 |
| Charge (mv) | <-27 |
| Total Atom Count | -73000000 |
| Surface Atoms (%) | -0.6 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Colon cancer; Liver cancer |
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