This product is a SU-DHL-6 B cell engineering tool based on the Nanoparticles (Anisamide/ Sigma receptors) delivery system and CRISPR-based (CCR5-SpCas9-NLS-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | SU-DHL-6 |
| Target | CCL2 |
| Insert Clone | BG-58E |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Mouse genome E-3 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Anisamide/ Sigma receptors |
| Active Agents | Thymoquinone |
| Particle Size | 20-3000 |
| Charge (mv) | -25 to -47 |
| Total Atom Count | -57,000,000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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