This product is a SU-DHL-10 B cell engineering tool based on the Quantum dots (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-227-crispr RNA-SpCas9-SCR7 pyrazine) genome editor.
| Host Cell | SU-DHL-10 |
| Target | CCP |
| Insert Clone | BG-81E |
| Safe Harbor Sites (SHS) | SHS-227 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-2 |
| Vehicles | Quantum dots |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | ≤10000 |
| Charge (mv) | <-25 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Breast cancer; Prostate cancer; Lung cancer; Ovarian cancer |
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