This product is a NCI-H929 [H929] B cell engineering tool based on the Liposomes (EGFR mAb/Epidermal Growth Factor Receptor) delivery system and CRISPR-based (SHS-321-tracr RNA-Cas9-RS-1) genome editor.
| Host Cell | NCI-H929 [H929] |
| Target | CCR2 |
| Insert Clone | BG-82E |
| Safe Harbor Sites (SHS) | SHS-321 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | RS-1 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Liposomes |
| Ligand/Receptor | EGFR mAb/Epidermal Growth Factor Receptor |
| Active Agents | Celastrol |
| Particle Size | 10-50 |
| Charge (mv) | 10 to 55 |
| Total Atom Count | -22,000,000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Colorectal cancer; Lung cancer |
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