This product is a Raji B cell engineering tool based on the Solid lipid nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (SHS-317-huIgH296-Cas9-L755507 ) genome editor.
| Host Cell | Raji |
| Target | CCR2 |
| Insert Clone | R6R100 |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | huIgH296 |
| Nuclease | Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | Regorafenib |
| Particle Size | 10-1000 |
| Charge (mv) | 0 to -16 |
| Total Atom Count | ~20,000,000 |
| Surface Atoms (%) | ~4 |
| Specific Surface Area (m2/g) | ~8 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Colorectal cancer; Lung cancer |
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