This product is a NCI-H929 [H929] B cell engineering tool based on the Gold nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (CCR5-tracr RNA-SpCas9-RS-1 ) genome editor.
| Host Cell | NCI-H929 [H929] |
| Target | CCR2 |
| Insert Clone | R6R85 |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | tracr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Mouse genome E-1 |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | <2500 |
| Charge (mv) | <-1 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Colorectal cancer; Lung cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.