This product is a Raji-Luc B cell engineering tool based on the Solid lipid nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-321-tracr RNA-Cas9-RS-1 ) genome editor.
| Host Cell | Raji-Luc |
| Target | CCR4 |
| Insert Clone | 406 |
| Safe Harbor Sites (SHS) | SHS-321 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | RS-1 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-3 |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | DOX |
| Particle Size | 10-500 |
| Charge (mv) | 6 to 92 |
| Total Atom Count | ~20,000,000 |
| Surface Atoms (%) | ~4 |
| Specific Surface Area (m2/g) | ~8 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Colon cancer; Lung cancer; Ovarian cancer |
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