This product is a HS-Sultan B cell engineering tool based on the Dendrimers (MUC1 aptamer/MUC1) delivery system and CRISPR-based (AAVS1-sgRNA-SpCas9-Nocodazole ) genome editor.
| Host Cell | HS-Sultan |
| Target | CD11b |
| Insert Clone | OKM2 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | sgRNA |
| Nuclease | SpCas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Dendrimers |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | DOX |
| Particle Size | 10-500 |
| Charge (mv) | <-25 |
| Total Atom Count | ~20,000,000 |
| Surface Atoms (%) | ~4 |
| Specific Surface Area (m2/g) | ~8 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer; Melanoma |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.