This product is a Raji-Luc2 B cell engineering tool based on the Micelles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (SHS-323-SpCas9-Cas9-RS-1 ) genome editor.
| Host Cell | Raji-Luc2 |
| Target | CD163 |
| Insert Clone | SP96 |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | SpCas9 |
| Nuclease | Cas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Human genome |
| Vehicles | Micelles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | <500 |
| Charge (mv) | 10 to 55 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | Baculovirus-AAV |
| Vector Name | BCpCDH4 |
| Targeting Diseases | Breast cancer; Colon cancer; Glioblastoma; Gastric cancer; Liver cancer |
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