This product is a Ramos (RA 1) B cell engineering tool based on the Niosomes (Fucoidan/P-selectin) delivery system and CRISPR-based (huROSA-26-sgRNA-SpCas9-L755507) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | CD20 |
| Insert Clone | BG-21E |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | sgRNA |
| Nuclease | SpCas9 |
| Enhancer | L755507 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-2 |
| Vehicles | Niosomes |
| Ligand/Receptor | Fucoidan/P-selectin |
| Active Agents | Paclitaxel, chlorin e6 |
| Particle Size | <2300 |
| Charge (mv) | -29 to -80 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Lung cancer; Breast cancer; Prostate cancer; Melanoma |
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