This product is a DG-75 [D.G.-75] B cell engineering tool based on the Quantum dots (Folate/ Folate Receptor) delivery system and CRISPR-based (hROSA26-crRNA:tracrRNA duplex-Cas12-(Z)-4-Hydroxytamoxifen ) genome editor.
| Host Cell | DG-75 [D.G.-75] |
| Target | CD24 |
| Insert Clone | 7H159 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | (Z)-4-Hydroxytamoxifen |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Quantum dots |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | ESC8 |
| Particle Size | 20-150 |
| Charge (mv) | 13 to 65 |
| Total Atom Count | ~60,000,000 |
| Surface Atoms (%) | ~0.8 |
| Specific Surface Area (m2/g) | ~2.5 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Colorectal cancer; Breast cancer; Lung cancer; Esophageal squamous cell carcinoma; Bladder cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.