This product is a Ramos (RA 1) B cell engineering tool based on the Magnetic nanoparticles (LRP-1 targetingpeptide/Lipoproteinreceptor-related protein-1) delivery system and CRISPR-based (SHS-323-crRNA:tracrRNA duplex-Cas12-RS-1 ) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | CD26 |
| Insert Clone | 7H111 |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Magnetic nanoparticles |
| Ligand/Receptor | LRP-1 targeting peptide/Lipoprotein receptor-related protein-1 |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | 10-50 |
| Charge (mv) | ≤50 |
| Total Atom Count | ~20,000,000 |
| Surface Atoms (%) | ~4 |
| Specific Surface Area (m2/g) | ~8 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.