This product is a RPMI 8226 B cell engineering tool based on the Solid lipid nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-227-tracr RNA-Cas9-Nocodazole) genome editor.
| Host Cell | RPMI 8226 |
| Target | CD276 |
| Insert Clone | BG-51E |
| Safe Harbor Sites (SHS) | SHS-227 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-8 |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | DOX |
| Particle Size | 15-188 |
| Charge (mv) | -1 to -20 |
| Total Atom Count | -57,000,000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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