This product is a SU-DHL-10 B cell engineering tool based on the Nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (AAVS1-crispr RNA-SpCas9-3'-Azido-3'-deoxythymidine ) genome editor.
| Host Cell | SU-DHL-10 |
| Target | CDK2 |
| Insert Clone | FFNH-336 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Human genome |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Bortezomib |
| Particle Size | <2500 |
| Charge (mv) | 17 to 58 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Lung cancer; Brain cancer; Colon cancer; Ovarian cancer; Liver cancer |
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