This product is a Ramos.2G6.4C10 B cell engineering tool based on the Nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-255-SpCas9-NLS-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Ramos.2G6.4C10 |
| Target | ERO1B |
| Insert Clone | B6CR206 |
| Safe Harbor Sites (SHS) | SHS-255 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | DOX |
| Particle Size | 20-150 |
| Charge (mv) | 6 to 86 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Lung cancer; Breast cancer; Prostate cancer; Melanoma |
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