This product is a DG-75 [D.G.-75] B cell engineering tool based on the Quantum dots (Dexamethasone/Glucocorticoid receptor) delivery system and CRISPR-based (hROSA26-huIgH296-Cas9-RS-1) genome editor.
| Host Cell | DG-75 [D.G.-75] |
| Target | FCMR |
| Insert Clone | BGR40 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | huIgH296 |
| Nuclease | Cas9 |
| Enhancer | RS-1 |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Quantum dots |
| Ligand/Receptor | Dexamethasone/Glucocorticoid receptor |
| Active Agents | ESC8 |
| Particle Size | 41-150 |
| Charge (mv) | 6 to 92 |
| Total Atom Count | -61000000 |
| Surface Atoms (%) | -0.7 |
| Specific Surface Area (m2/g) | -3.6 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Colon cancer; Glioblastoma; Gastric cancer; Liver cancer; Lung cancer |
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