This product is a SU-DHL-6 B cell engineering tool based on the Sphingosomes (Anisamide/ Sigma receptors) delivery system and CRISPR-based (CCR5-SpCas9-SpCas9-RS-1) genome editor.
| Host Cell | SU-DHL-6 |
| Target | FLT1 |
| Insert Clone | BG-94E |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | SpCas9 |
| Nuclease | SpCas9 |
| Enhancer | RS-1 |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Sphingosomes |
| Ligand/Receptor | Anisamide/ Sigma receptors |
| Active Agents | Bortezomib |
| Particle Size | <100 |
| Charge (mv) | 8-55 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Colon cancer |
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