This product is a Ramos (RA 1) B cell engineering tool based on the Solid lipid nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-291-SpCas9-SpCas9-3'-Azido-3'-deoxythymidine ) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | GPC3 |
| Insert Clone | 15G1 |
| Safe Harbor Sites (SHS) | SHS-291 |
| gRNA | SpCas9 |
| Nuclease | SpCas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | DOX |
| Particle Size | ≤10000 |
| Charge (mv) | 6 to 92 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Non-small cell lung cancer; Prostate cancer; Liver cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.