This product is a Raji-Luc B cell engineering tool based on the Niosomes (EpCAM aptamer/Epithelial celladhesion molecule) delivery system and CRISPR-based (SHS-323-crRNA:tracrRNA duplex-SpCas9-SCR7 pyrazine) genome editor.
| Host Cell | Raji-Luc |
| Target | MS4A7 |
| Insert Clone | B6CR628 |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | SpCas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Niosomes |
| Ligand/Receptor | EpCAM aptamer/Epithelial cell adhesion molecule |
| Active Agents | DOX |
| Particle Size | 10-50 |
| Charge (mv) | <-1 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Lung cancer; Brain cancer; Colon cancer |
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