Products
In the fields of diagnostics, therapeutics, and fundamental life sciences, the ability to create precise, stable linkages between biomolecules is paramount. Bioconjugation (the chemical strategy of linking proteins, peptides, nucleic acids, and other molecules) is the foundational technology that powers discoveries ranging from novel cancer therapies to high-sensitivity diagnostic assays.
At Creative Biolabs, we specialize in providing high-purity, reliable, and innovative reagents that meet complex bioconjugation demands. Our portfolio is engineered to provide you with robust tools for linking, labeling, and delivering, ensuring that your results are reproducible and your projects advance. As you navigate the complexities of your research, how are you ensuring the stability and functionality of your molecular conjugates?
Applications: From Discovery to Therapeutics
The right bioconjugation tools are critical for translating ideas into functional applications. Our reagents are designed to support the full spectrum of research and development, enabling groundbreaking work across multiple disciplines.
Driving Therapeutic Innovation
The development of targeted therapies, such as Antibody-Drug Conjugates (ADCs), relies on the precise linkage of a cytotoxic payload to a monoclonal antibody. This requires sophisticated crosslinkers and, often, targeting peptides to enhance specificity. Similarly, our Cell-Penetrating Peptides (CPPs) are pivotal for intracellular drug delivery, providing a mechanism to transport novel biologic cargos (like proteins or nucleic acids) across cellular membranes.
Illuminating Biological Processes
Understanding complex biological pathways requires tools that can label and trace molecules without interfering with their function. Our high-performance fluorescent reagents offer exceptional brightness and photostability, ideal for applications like flow cytometry, high-content screening, and advanced cellular imaging. These tools enable researchers to visualize cellular events in real-time with unparalleled clarity.
Enhancing Diagnostic Sensitivity
The performance of modern immunoassays, such as ELISA and Western blotting, depends on the quality of the detection reagents. Our crosslinkers are used to create stable enzyme-antibody conjugates, while our fluorescent dyes provide the bright, stable signals needed for next-generation multiplexed diagnostic platforms.
Are you developing a novel ADC or a high-sensitivity diagnostic assay? Discover how our reagents can provide the precision you need.
Our Bioconjugation Portfolio
We offer a comprehensive selection of reagents organized to meet your specific technical needs. Each product line is characterized by high-purity standards and rigorous quality control, providing the reliability your research demands.
01. Crosslinkers: The Architectural Tools
Our comprehensive portfolio of crosslinkers provides the essential tools for creating stable covalent linkages for applications ranging from protein-protein interaction studies to antibody labeling and surface immobilization. We offer a diverse array of reagents structured by functionality, including homobifunctional linkers for simple polymerization and heterobifunctional linkers (e.g., NHS-Maleimide) for controlled, sequential conjugations. To meet specific application demands, our selection includes cleavable linkers (e.g., disulfide-based) for release studies, non-cleavable options for maximum stability, and advanced PEGylated spacers designed to improve conjugate solubility, reduce aggregation, and decrease immunogenicity.
02. Fluorescent Reagents: High-Performance Labeling
We provide a superior collection of high-performance fluorescent reagents engineered for demanding imaging and detection applications. These reagents deliver the exceptional brightness and photostability required for advanced protocols. Our portfolio covers the full spectrum, from UV to near-infrared (NIR), ensuring compatibility with any instrument. To facilitate robust and efficient conjugation to proteins, antibodies, and nucleic acids, our dyes are available with a wide array of functional groups, including NHS esters, maleimides, azides, and alkynes.
03. Peptides: Specificity in Targeting and Delivery
Our peptide portfolio provides highly versatile functional tools for advanced bioconjugation, offering sophisticated mechanisms for cellular access and target-specific binding. This includes our potent Cell-Penetrating Peptides (CPPs), which are designed to efficiently transport a wide range of impermeable cargo—such as proteins, siRNA, and nanoparticles—across cellular membranes. Complementing these are our high-affinity Targeting Peptides, which function as "molecular guides" to bind to specific cell-surface receptors (e.g., those overexpressed on tumor cells), thereby concentrating therapeutic or imaging agents precisely at the site of interest.
Contact Our Technical Experts
Your bioconjugation challenge is unique. At Creative Biolabs, we are more than a reagent supplier; we are your technical partners. Our team of specialists is available to help you troubleshoot protocols, select the ideal reagents, and discuss custom synthesis possibilities to meet your specific research goals.
Ready to discuss your project's specific challenges? Contact our technical support team today to optimize your bioconjugation strategy and accelerate your discovery.